MicrofluidicsHow fluid behaves on the microscale
Microfluidics is used to manipulate fluids on microscopic scales. This is useful as a platform to isolate and examine cells, study diseases and build model versions of the human body like a kidney on a chip! The devices are made using conventional clean-room based microfabrication processes.
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Dynamic Interface PrintingUltrafast, high-resolution 3D bioprinting
Published in the journal Nature, Dynamic Interface Printing (DIP) is our innovative 3D printing technique that utilizes an acoustically modulated air–liquid interface to rapidly create complex, support-free structures. In this method, a hollow print head with a transparent glass window at the top is employed. Light patterns are projected onto the meniscus—the curved surface of the liquid resin—formed at the open end of the print head. Acoustic vibrations stimulate steady flow of the resin across the meniscus, facilitating rapid polymerization and layer formation. This approach enables the fabrication of intricate lattice structures and centimeter-scale hydrogels with features as small as 30 micrometers. The DIP technique offers potential applications in biofabrication and microfluidic device manufacturing.
https://www.nature.com/articles/s44222-024-00271-5 |
Additive Manufacturing3D printers are taking over the world with their ability to build complex parts with incredible ease
Additive manufacturing is expanding in all directions! People are 3D printing houses, rocket engines, turbines, toys, even skin! We're looking at the microscale where we use novel techniques to 3D print tiny structures for our experiments!
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AcousticsMoving cells and particles with sound!
Our lab specializes in manipulating particles and cells using ultrasound. We have a lot of expertise in modelling and experimenting with acoustic waves in microscale systems. We can use acoustic waves to pattern and sort cells depending on their stiffness and density.
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MechanogeneticsEnabling cells to sense sound, pressure and flow!
We are interested in exploring how cells can sense mechanical stimuli and how this knowledge can be used to manipulate cells and brain areas. In our lab we develop ultrasound and fluidic devices to deliver mechanical stimuli to cells and use genetically modified cells to investigate mechanosensitive proteins.
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Great ExperimentsAsking the right questions in the laboratory and being prepared create the environment needed to succeed
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Targeted SimulationsSimulations are a powerful tool, knowing how and when to best use them gives the most effective results
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Analytical understandingAnalysis and approximation give us insight into the underlying causes of the phenomena we observe
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